Search academic texts

Information × Registration Number 0120U103984, ( 0221U101805  0221U106001  0221U106970  0223U004701  ) R & D request Title Latent carbenes for organic synthesis Head Kostyuk Oleksandr M., Registration Date 24-09-2020 Organization Institute of Organic Chemistry NAS of Ukraine popup.description1 The aim of the project is to create a new unprecedented type of reagents with unique properties that exist in the chemical equilibrium of the main neutral and carbene forms. Conducting research using DFT calculations to determine the structural and electronic factors that affect the balance of basic and carbene forms, and their reactivity. Study of the chemical properties of reagents, which are due to both forms. Study of the reactivity of the obtained compounds in typical reactions for carbenes, such as inserting into the CH bond of different hybridization (sp, sp2 and sp3). Elucidation of the reactivity of carbenes in reactions with substituted benzenes to determine the reaction rate, the relationship to functional groups and their effect on orientation and find out which solvents are suitable for use. popup.nrat_date 2024-12-10 Close