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Information × Registration Number 0121U109941, ( 0222U003506  0223U001038  ) R & D request Title Photocontrolled analogues of natural cytotoxic peptides for immunotherapy of metastatic cancer Head Komarov Ihor V., Доктор хімічних наук Registration Date 18-03-2021 Organization Taras Shevchenko National University of Kyiv popup.description1 Peptides that, when activated in tumors, will cause immunogenic cell death and, as a result, a powerful immune system response that can be used in innovative approaches to cancer immunotherapy. These peptides will be analogs of natural peptides and will have a photoisomerizable fragment (phototwitch) embedded in the polypeptide chain. The phototwitch is capable of reversible photoisomerization under the action of non-ionizing, red light. The configuration of the compounds changes between two forms, which will be called "closed" (inactive) and open (activated by light). popup.nrat_date 2024-12-09 Close