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Information × Registration Number 0121U110903, R & D request Title Computer modeling of therapeutic proteins and their nanocomposite complexes with using grid technologies and artificial intelligence Head Korneliuk Oleksandr I., д.б.н. Registration Date 05-05-2021 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description1 The aim of the project is to conduct computer modeling of the structure and molecular dynamics of therapeutic proteins and their nanocomposite complexes using grid technologies and artificial intelligence. The Department of Protein Engineering and Bioinformatics of IMBIG conducts research on antitumor proteins EMAR II, C-module of tyrosyl-tRNA synthetase and AIMP / p43 protein and their nanocomposite complexes. It should be noted that these proteins belong to the internal unstructured proteins, which are not available for study by X-ray diffraction analysis of crystals.The only possibility to study such complexes is computer modeling of their spatial structure and intramolecular dynamics, which determines their function. popup.nrat_date 2024-12-09 Close