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Information × Registration Number 0122U001862, ( 0223U001834  0224U031766  0225U003768  ) R & D request Title New biomimetic catalysts for the cleavage of nucleic acids, organophosphorus ecotoxicants and analogues of toxic warfare agents Head Vadym O. Pavlenko, Доктор хімічних наук Registration Date 21-02-2022 Organization Taras Shevchenko National University of Kyiv popup.description1 Development of scientifically sound approaches to the creation of functional materials based on complexes of transition metals with polynucleative ligands - derivatives of 1H-pyrazole, which would be highly effective catalysts for the cleavage of compounds with phosphoester bonds; development of methods for the synthesis of mono- and binuclear coordination compounds of transition metals based on chelated and binuclear ligands of the pyrazolate type, study of the relationship between their molecular structure, nature of metal ions, physicochemical (spectral, magnetic, electrochemical) parameters and catalytic efficiency cleavage of phosphoesters and development on this basis of a strategy for creating a new generation of highly efficient catalysts for hydrolytic cleavage of compounds with phosphoester bonds. popup.nrat_date 2024-12-09 Close