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Information × Registration Number 0123U102324, ( 0225U001999  0225U002434  ) R & D request Title Secondary metabolites of microorganisms with antibiotic, proteolytic and glycolytic action: patterns of macromolecule organization, functional and biological activity, ways of modification and stabilization, aspects of practical use Head Varbanets Liudmyla D., д.б.н. Registration Date 25-04-2023 Organization Institute of Microbiology and Virology named after D. K. Zabolotny of the National Academy of Sciences of Ukraine popup.description1 The aim of the work is to develop the fundamentals of obtaining microbial antibiotics, proteases, and glycosidases for the creation of technology for obtaining competitive drugs for medicine and the food industry. In order to realize this goal, the ways of production of secondary metabolites by microorganisms will be investigated, the catalytic properties of enzymes and their substrate specificity will be studied, the mechanisms of inactivation and stabilization by chemical modification will be established, the bundles of related genes for the biosynthesis of secondary metabolites in the genomes of streptomycetes will be studied. popup.nrat_date 2024-12-09 Close