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Information × Registration Number 0124U000637, ( 0225U003465  0226U002376  ) R & D request Title Immunological properties of the novel 2D nanomaterials MXenes Head Kyrylenko Serhii D., Кандидат біологічних наук Registration Date 22-01-2024 Organization Sumy State University popup.description1 The goal of the project is to determine the long-term effects of MXenes under conditions in-vivo. To achieve the goal, it is necessary to fulfil the following tasks: 1) establish processes of possible recognition of MXenes and their complexes as foreign agents by components of the innate immune system (including macrophages). 2) establish the possibility of phagocytosis of MXenes and their complexes with their subsequent processing. 3) establish the potential immunogenicity of MXenes as haptens and their complexes with proteins as antigens. 4) find out whether peptide-MXene complexes are presented by antigen-presenting cells after introduction of MXene into living systems. 5) establish the general patterns of in-vivo modulation of immune system parameters by MXenes. 6) establish of the possibility of induction of allergic hypersensitivity reactions to MXenes and their components popup.nrat_date 2024-12-09 Close