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Registration Number

0124U001685, ( 0225U004202  ) R & D request

Title

Molecular and genetic mechanisms of neurodegeneration in mouse brain involving proinflammatory cytokines in the modeling of posttraumatic stress disorder

Head

Dosenko Viktor Ye., Доктор медичних наук

Registration Date

13-02-2024

Organization

Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine

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The aim of the study is to establish the pathogenetic significance of non-coding RNAs, hypoxia-inducible factor, senescent cells and neuroinflammation in PTSD and to evaluate the effectiveness of experimental therapy of this disease using intermittent hypoxia-hyperoxia and specific inhibitors of HIF prolyl hydroxylase.

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2024-12-09