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Information × Registration Number 0202U002140, 0197U004373 , R & D reports Title Study of mechanisms of action and regulation of fibrinolytic system by modification of plasminogen popup.stage_title Head Kudinov S.O., Registration Date 31-01-2002 Organization A.V.Palladin Institute of Biochemistry of National Academy of Sciences popup.description2 The experiment al substantion has been presented in relation to possibility of developing some new thrombolytic preparations possesing by assigned prolongation period of action on the base of polymeracylated derivatives of plasminogen-streptokinase complex.The theoretical concept of thrombolytic therapy fulfilment has been created in relation to fibrinolytic process mechanism as well as utilizing as a thrombolytic of the plasminogen preparation or plasminogen combined low physiologic doses of tissue activators. The basic scheme of affine sorbents photochemical synthesis has been developed and some sorbents complying with main reguirements of affine chromotography for plasminogen isolation from human blood plasma have been produced Product Description popup.authors popup.nrat_date 2020-04-02 Close