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Information × Registration Number 0204U003152, 0101U000954 , R & D reports Title Experimental study of pineal gland role in the atherogenesis processes popup.stage_title Head Bondarenko Ludmila Olexandrivna, Registration Date 10-02-2004 Organization V.Danilevsky Institute of Endocrine Pathology Problems Academy of Medical Sciences of Ukraine popup.description2 Object of research: the object of analysis is a sexual mature 'shinshila' rabbits. The purpose is experimental to determine the role of oppression of the function to give birth melatonin of the pineal gland in violations of the hormonal homeostasis and realization of mechanisms of atherosclerosis damages development. Methods: physiological, biochemical, radioimmunological, immunofermentical, fluorimetrical, histological, electronmicroscopic. Determined, that braking of function to give birth melatonin of the pineal gland by light is a powerful factor, that causes hormonal and structural modifications in seminifics, thyroid and adrenal glands makes worse morphofunctional heart condition, aorta, liver and kidneys and additional load of cholesterin accelerates and intensifics the destructive processes in this organs, that give a reason to consider hypopinealism like a starting mechanism of accelerate "malignant" atherosclerosis development. The replace therapy by melatonin improves (but no reestablish) that index. The field of application: endocrinology, cardiology, therapy Product Description popup.authors popup.nrat_date 2020-04-02 Close