Search academic texts

Information × Registration Number 0204U003220, 0101U002025 , R & D reports Title To study the mechanisms of rats lifespan prolongation by liver microsomal monooxygenases enzyme imprinting with phenobarbital. popup.stage_title Head Bezrukov Vladislav Viktorovich, Registration Date 18-02-2004 Organization Institute of Gerontology Acad. Med. Sci Ukraine popup.description2 It is shown that the principal mechanisms of female rats lifespan prolongation under the condition of phenobarbital induced hepatic microsomal oxygenases enzyme imprinting are as follows: the extent of cytochrome P-450 inductive synthesis and isoform profile alterations, the lack of chemical cancerogenesis probability augmentation, the decrease of cholesterol concentration and the accompanying rise of estradiol level. Product Description popup.authors popup.nrat_date 2020-04-02 Close