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Information × Registration Number 0205U000460, 0102U004410 , R & D reports Title Biophysical mechanisms of influence of the nano-microscopic and microscopic structure of neurons on the dynamics of effectiveness of dendritic fields popup.stage_title Head Korogod Sergiy Mykhajlovych, Registration Date 28-01-2005 Organization Dniepropetrovsk national university popup.description2 Object: mathematical models of single synaptic contacts and neurons with reconstructed morphologically complex dendritic arborisations and distributed tonically activated synapses. Aim: to reveal biophysical mechanisms defining the synaptic efficacy changes due to nano-structural changes in synapses and in population of synaptic and extra-synaptic membrane by ion channels, which are critical for dynamics effective dendritic fields. For the first time, it is established that changes in efficacy of a synapse can result from electrodiffusional redistribution of charged transmitter in the electric field created in the synaptic cleft by a current through receptor channels. Area of use - biophysics, physiology of the nervous system, neurocomputers and related fields. Product Description popup.authors popup.nrat_date 2020-04-02 Close