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Information × Registration Number 0206U000162, 0101U000361 , R & D reports Title Molecular genetic investigation of mutations determined for monogenic hereditary diseases and hereditary susceptibility to multifactorial pathology popup.stage_title Head Livshits Ludmila, Registration Date 17-01-2006 Organization Institute of molecular biology & genetics popup.description2 The role of some types of mutations in monogenic and multifactorial diseases proliferation has been determined. It has been clarified that HFE is the Cystic Fibrosis gene-modifier, on the other hand, this gene may be the factor of hereditary susceptibility to glioblastoma, hepatitis, pancreatit and type II diabetes in iron exogenous overload conditions. It has been shown that CFTR, SMN and some X- and Y-chromosome genes are involved in different forms of male and female infertility. Effective methods of diagnosis and prevention of these hereditary diseases in high-risk groups have been proposed. Product Description popup.authors popup.nrat_date 2020-04-02 Close