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Information × Registration Number 0206U000664, 0103U001404 , R & D reports Title Mechanisms of induction of anti-proliferative and cytotoxic activity in normal and transformed cells popup.stage_title Head Stoyka Rostyslav Stepanovych, Registration Date 02-02-2006 Organization Institute of cell biology, National Academy of Sciences of Ukraine popup.description2 Mechanisms of cytotoxic activity of macrophage against transformed cells, as well as possible methods of their modulation were studied. The effect of some anticancer drugs on the tumor cells' ability of transforming growth factor beta (TGF beta) production and expression of signaling proteins of Smad family were investigated. Some cellular and molecular mechanisms of alkaloids' and triterpenes' action on immunocompetent and tumor cells were also studied. The above mentioned substances were isolated and refined in our department. Product Description popup.authors popup.nrat_date 2020-04-02 Close