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Information × Registration Number 0207U000566, 0104U002202 , R & D reports Title To study day's rhythm of endocrine glands function and lipid metabolism nith hypopinealism popup.stage_title Head Bondarenko Ludmila Olexandrivna, Registration Date 26-01-2007 Organization V.Danilevsky Institute of Endocrine Pathology Problems Academy of Medical Sciences of Ukraine popup.description2 Object of research: epiphysis, hypophysis, thyroid gland, pancreas, sexual glands, blood of sexually mature males of rabbit of breed "shnshilla". The purpose - to establish value of levelling of night peak of melatonin in meachanism of polyendocrinopatys and dyslipidemia development. Methods: biochemical, radioimmunological, immunoenzymatic, histological, morfometrical, statistical. Reveaied morphofunctional pathlogical changes of adenohypophysis and mediate hypophysis, abnormalities of day-night rhythms of hormonal activity thyroid, pancreas and sexual glands and alse rates of carbohydrate and lipide metabolism in rabbits with hypopinealism. Elaborated method of early diagnostics of the as for manifestations forms of an atherosclerosis and a diabetes is developed. The expediency of application of drugs melatonin is theoretically justified at a hypothyroidism, a hypogonadism and at failure of cells of a pancreatic gland induction of hypopinealism. Range of application: endocrinology, pharmacology,therapy. Product Description popup.authors popup.nrat_date 2020-04-02 Close