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Information × Registration Number 0207U002537, 0103U001409 , R & D reports Title The comparative characteristic of features cd34 + cells of a various parentage for the further substantiation of expediency of their use at auto- and allotransplantations. popup.stage_title Head Bebeshko Volodimir Grigorovich, Registration Date 05-02-2007 Organization Research Centre for Radiation Medicine popup.description2 Object of research - mononuclears of bone marrow, cord blood, peripheral blood and fetal liver. The aim of research is the substantiation and optimization of use of hematopoietic cells received from bone marrow, cord blood, peripheral blood and fetal liver for auto and allogenic transplantation in patients with oncological and oncohematological pathology on the basis of realization comparative analysis of morphofunctional and immunogenetic properties of these cells. Methods of research - morphological, immunological, cytochemical, immunogenetical, cytogenetical, molecular and cultural. It is established, that the hemopoietic cells received from bone marrow, peripheral, cord blood and fetal liver have high proliferation potential and can be considered as a source for carrying out of transplantation. In comparative aspect the greatest quantity of stem cells is determined in samples a fetal liver, cord blood in comparison with a bone marrow and peripheral blood. The approach which includes stage-by-stage purpose cytostatic preparations in high dozes, assignment cytokines and separation of stem cells from blood a method hardware cytoferezis leads to a successful collection of cells in the quantity necessary for carrying out of transplantation. The most perspective source for further use in quality hallo and autotransplantation is cord blood. Product Description popup.authors popup.nrat_date 2020-04-02 Close