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Information × Registration Number 0209U005446, 0108U007079 , R & D reports Title Development of laboratory method of the synthesis of azydothymidine. popup.stage_title Head Shkaraputa L., Registration Date 17-02-2009 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The laboratory synthesis of 3'-azidothymidine (AZT) is conducted according to a scheme : thymidine > 5'-О-benzoylthymidine > 3'-О-mezyl-5'-О-benzoylthymidine > 5'-О-benzoyl-2,3'-anhydrothymidine > 5'-О-benzoyl-3'-N3-thymidine > 3'-azido-3'-dezoxythymidine. The methods of stage by stage control of azidothymidine synthesis are developed. It is established by the masses-spectrums, that content of AZT in a sample more than 98%. Laboratory regulation of azidothymidine obtaining is developed. Yield of AZT is more than 40%, considering on an initial thymidine.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close