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Information × Registration Number 0209U005859, 0105U003236 , R & D reports Title Exploration of the mechanisms of immune pathology of the liver and female reproductive system and the wais of its correction popup.stage_title Head Alexeyeva Iryna Mykolayivna, Registration Date 03-06-2009 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Some mechanisms of immune damage of the liver and female reproductive organs (ovary, uterus), dealing with the differentiated action of immunocompetent cells, antibodies and cytokines have been investigated. Protective effect of the inhibitors of the nuclear transcriptional factor NF-kB in immune damage of the liver of Т-cellular genesis was revealed. It has been established that an application of antiovarian antibodies and proinflammatory cytokines depressed ооgenesis in mice and promoted destruction of the follicular cells of a around ооcytes. An impairment in mitochondrial functions was involved in those immune factor effects. Product Description popup.authors popup.nrat_date 2020-04-02 Close