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Information × Registration Number 0209U006056, 0106U001578 , R & D reports Title Studying of a role of membrane generation of active forms of oxygen in life span determining mechanisms popup.stage_title Head Padalko V.; Lemeshko V., Registration Date 20-01-2009 Organization Kharkov national university named after V.N. Karazin popup.description2 The objects of study were subcellular fractions of liver, homogenates of liver, heart and brain and serum of blood of 4-months old males and 14-15-months old females Wistar rats, homogenates of imago of Drosophila melanogaster (Oregon-R and White strains). The results of the present report are indicative of prospective of uncoupling substance as 'geroprotectors" of the future, though manipulations with mitocondria's systems are able to damage maintenance of high activity of oxidative phosphorilation for ensuring of cell's power imputs. This fact can explain positive effect of DNF on vitality of drosophila in normal conditions and negative effect of DNF on vitality of drosophila in inferior living conditions. The effect of intensity of active oxygen species generation on the rate of aging and possibilities of aging slowing by means of correction of efficacy and intensity of function of membrane-bound systems of electron transport were investigated. The possibility of life span and vitality correction in living organisms by the ubstances received from the plant which affected on intensity of endogenous active molecules oxygen generation was established. Product Description popup.authors popup.nrat_date 2020-04-02 Close