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Information × Registration Number 0211U000999, 0110U005552 , R & D reports Title Investigation of tumor microenvironment modifying effect on magnetization, dispersity, biocompatibility and stability of magnetic fluids on the basis of complex ferromagnetic oxides popup.stage_title Head Osynsky Sergy Petrovych, Registration Date 15-03-2011 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Nanoparticles of manganites La1-xAxMnO3 by precipitation method from solutions and barium hexaferrite that are not toxic and do not display the side effects in experimental animals. Administration of nanoparticles into tumor has not resulted in the alteration of structure both of tumor and normal tissues. It was shown that nanoparticles penetrate into tumor cells, induce apoptosis and rearrangement of protein-synthesizing apparatus. Observed effects of nanoparticles are more significant in hypoxic tumors and low extracellular рН. Product Description popup.authors Бубновська Лариса Микитівна В'юнов Олег Іванович Ганусевич Ірина Іванівна Ковельська Антоніна Василівна Мамонтова Леся Анатолівна Пашкова Олена Володимирівна Сергієнко Тетяна Карлівна Солов'єва Катерина Дмитрівна Солопан Сергій Олександрович popup.nrat_date 2020-04-02 Close