Search academic texts

Information × Registration Number 0211U007503, 0109U008621 , R & D reports Title The role of the biological active substances in the regulation of the physiological functions in the norm and at the different pathological stations. popup.stage_title Head Sobolev Valeriy Ivanovich, Registration Date 31-05-2011 Organization Donetsk National University popup.description2 The purpose of the work is being the study of peculiarities of humoral mechanisms of regulation of physiological functions and, in particular, the role of different natural biologically active substances, its synthetic analogues, blockades of receptors of humoral factors and the interaction between them in the regulation of functional state of neural-muscular and hypophysis-thyroid systems and psychoemotional status of animals. Methods of research: electromyography and ergography in situ, immunofermentic analyzer, ethological methods. These have been developed and created: - the method of reproduction at the animals of hypercortisolism and hyperthyroid states, hyperandrogenicity, hypothermia, influences of the moderate physical loading; - the electromyography and ergography methods in situ; - the experimental researches have been conducted and the experimental material has been statistically treated and analyzed by the study of energy of muscular contraction in the dynamics of chronic introduction of dexamethasone, complex application of dexamethasone and moderate physical loading, development of state of hypothermia; - the experimental researches have been conducted and the material has been analyzed by the study of correlations between the level of triiodothyronine and thyroxin at the white rats in norm and at experimental hyperthyroisys; - the ethological reactions of animals have been studied in the conditions of the changed noradrenergic transmission in cerebrum taking into account their initial emotional status. Keywords: dexamethasone, solitary muscular contraction, latent period of excitement, phases of the solitary contraction of the muscle, the amplitude of muscular contraction, the frequency of the muscle's tetanization, the maximal steady capacity of the muscle, the duration of the muscle's "inworking", thyroid, hyperthyroisys, hormonal correlations, hypothermia, temperature effect of muscular contraction, noradrenergic transmission, ethological reactions. Product Description popup.authors Алієва Гульнара Фазіл кизи Дерев'янченко Ірина Анатоліївна Капланец Ірина Вікторівна Попов Володимир Федорович Станішевська Тетяна Іванівна Труш Віктор Іванович Труш Віра Володимирівна Фролова Галина Олександрівна popup.nrat_date 2020-04-02 Close