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Information × Registration Number 0212U001015, 0111U004969 , R & D reports Title Monitoring of omega-3 index and disclosure the novel mechanisms of omega-3 fatty acids actions involved in cardiac disease and arrhythmia prevention popup.stage_title Head Moybenko Olexij Olexijovych, Registration Date 05-01-2012 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 The investigations revealed that the use of preliminary omega-3 PUFAs in ischemia-reperfusion prevents the decrease expression of the protein caveolin-1 and connexin-43 and thereby cell-to-cell communication that may be essential for prevention of arrhythmias onset. Our results indicate that culture of cardiomyocytes from rats with prenatal omega-3 PUFA application after anoxia-reoxygenation contains more living cells than control group and respectively less number of apoptotic and necrotic cells. It was shown that omega-3 PUFA elevated fatty acid transport protein and interleukin-1 receptor antagonist mRNA expression in adult rats' tissues and isolated cardiomyocytes. Product Description popup.authors А. М. Шиш А.С. Жуковська В.С. Нагібін О.О.Мойбенко Ю.Т. Стрєлков popup.nrat_date 2020-04-02 Close
R & D report
Monitoring of omega-3 index and disclosure the novel mechanisms of omega-3 fatty acids actions involved in cardiac disease and arrhythmia prevention
Head: Moybenko Olexij Olexijovych. Monitoring of omega-3 index and disclosure the novel mechanisms of omega-3 fatty acids actions involved in cardiac disease and arrhythmia prevention. (popup.stage: ). Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine. № 0212U001015
1 documents found

Updated: 2026-03-17


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