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Registration Number

0212U005729, 0112U003653 , R & D reports

Title

Genetic variability investigation of liver flukes of Opisthorchiidae family in natural foci of opisthorchiidiases in Russian Federation and Ukraine

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Head

Yevtushenko Andriy,

Registration Date

26-12-2012

Organization

Nationali Scientific Center "Institute of Experimental and Clinical Veterinary Medicine"

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Object of research - opisthorchid flukes, parasites, fish, genome, mollusks, carnivorous, water objects. Purpose of work - to identify and estimate by a set of genetic markers the genetic diversity of Trematoda family Opisthorchiidae - Opisthorchis felineus, Metorchis bilis, Pseudamphistomum truncatum, Metorchis xantosomus and to provide a basis for a multilateral and complex research on gene systematics, molecular parasitology, molecular epidemiology of liver flukes. Research Methods - parasitological, biological, microscopic, molecular genetic, epizootological. The first population genetic analysis of Siberian and Ukraine liver fluke revealed its uniquely low genetic diversity across geographically enormous range. We suggest that severe geoclimatic events during the Quaternary epoch led to virtually complete extinction of this species. Upon completion of the last glaciation, O. felineus underwent rapid expansion from a single ancestral population. In fact, this ancestral population could have been very small, due to the ability of this parasite to reproduce clonally. Importantly, low genetic diversity of this parasitic species appears to have had no impact on its adaptivity, which is supported by its wide present-day distribution range and high infestation rate of hosts across the entire territory.

Product Description

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Євтушенко Інна Дмитрівна
Герілович Антон Павлович
Солодянкін Олексій Сергійович
Стегній Антон Борисович

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2020-04-02