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Registration Number

0212U006485, 0108U003816 , R & D reports

Title

The investigation of methods of molecular diadnostics of tumours of haematopoetic and limphoid tissues

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Head

Gluzman Daniil Fishelevich, Доктор медичних наук

Registration Date

18-04-2012

Organization

R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology

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The aim of work consisted in identification of algorithm of diagnostic laboratory researches in myeloid hemoblastoses: acute myeloid leukemias (AML) and chronic myeloproliferative diseases (CMPD) including chronic myeloid leukemia (CML). Based on the results of the study in 171 AML patients, the diagnostic algorithm was delineated comprising basic clinical-hematological and morphocytological, cytochemical and immunocytochemical features of pathological cells and molecular-genetic peculiarities for detection of specific chromosomal abnormalities underlying AML forms with varying clinical patterns and different prognosis. The diagnostic algorithm of the primary diagnostics of CML and differential diagnosis between CML and other CMPD was realized in 27 and 21 cases, respectively.

Product Description

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Іванівська Тетяна Степанівна
Арсень Марія Миколаївна
Воронович Тетяна Володимирівна
Коваль Стелла Володимирівна
Надгорна Валентина Олександрівна
Полудненко Людмила Юріївна
Скляренко Лілія Михайлівна
Українська Наталія Іванівна
Шаповал Євгенія Іванівна

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2020-04-02