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Information × Registration Number 0212U007429, 0111U010258 , R & D reports Title Improvement of technology of purification of immunoglobulins for intravenous application from ballast peptides. popup.stage_title Head Timchenko A.S., Registration Date 26-12-2012 Organization Kiev Research Institute of Haematolojy and Blood Transfusion popup.description2 Object of research -- the human intravenous immunoglobulin. Aim of research - to define the main technological parameters for the prevention of molecular aggregation of intravenous immunoglobulin and for the lowering of anticomlement activity on the stage of its manufacture. Methods of research - the method of fractionation of blood plasma by Cohn, chromatography, immunochemical, immunological, biochemical, biological, statistic. It is worked the technology of manufacture of the human intravenous immunoglobulin (IVIG) and obtained the 1-st series of preparate. It is investigated the main physical and chemical properties, molecular parameters, anticomplement activity, biological properties and purity degree of IVIG.The resultes of investigate showed the technological process of the manufacture of IVIG needs the further improvement for the lowering of the immunoglobulin A and M. Branch of application - medicine, biotechnology. Product Description popup.authors Вергун Л.Ю. Загородня Ю.О. Сергутіна С.Ю. popup.nrat_date 2020-04-02 Close