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Information × Registration Number 0213U004795, 0113U005097 , R & D reports Title Molecular design, synthesis and research of inhibitors of protein tyrosine phosphatases as potential medicinal agents for diabetes and other diseases. Section 1. Molecular design and researches in vitro of inhibitors of protein tyrosine phosphatases as potential medicinal agents. popup.stage_title Head Vovk A., Registration Date 26-12-2013 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Computer searching of inhibitors of protein tyrosine phosphatase 1B with use of a database of synthetic nitrogen containing heterocycles is executed. New derivatives of 2-thioxo-1,3-thiazolidine-4-one as potential inhibitors of РТР1В were synthesised and their properties were studied in systems in vitro. For the first time the influence of monoesthers of thiacalixarene phosphonic acids on activity РТР1В and others therapeutically important protein tyrosine phosphatase was established. Product Description popup.authors І.М. Міщенко В.Ю. Танчук Л.А. Кононець О.В. Музичка С.Г. Пільо popup.nrat_date 2020-04-02 Close