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Information × Registration Number 0214U003425, 0111U002012 , R & D reports Title Determination of the effectiveness of therapy of pegylated interferon in combination with nucleoside analogues in patients co-infected HCV / HIV and HBV / HIV popup.stage_title Head Fedorchenko S.V., Registration Date 31-01-2014 Organization The L.V. Gromashevsky Institute of Epidemiology and Infectious Diseases AMS of Ukraine popup.description2 .Research aim - to define efficiency of therapy пегилированным inter- Pheron( Piebald - ИФН) in combination with нуклеозидными analogues for patients with to - by the infection of ВГС / ВИЧ and ВГВ / of HIV.Research object - the infection caused by HIV and ВГС is united.Article of research -? patients to -инфекцией HIV / of ВГС ;? biological субстраты(blood, serum, plasma of blood) of patients to -инфекцией HIV / of ВГС ;? histories of illnesses of patients with to - by the infection of HIV / ВГС ;? клинико -лабораторные displays of chronic hepatitis With( ХГС ) for patients with to - by the infection of HIV / ВГС ;? клинико -лабораторные displays of HIV of -инфекции for patients with to - by the infection of HIV / ВГС ;? factors of influence on efficiency of antiviral therapy( ПВТ ) for patients with to - by the infection of HIV / ВГС ;? efficiency of treatment of ВГС for patients with to - by the infection of HIV / ВГС.Research methods are a физикальное inspection of patients, laboratory ме- a тоды( общеклинические, biochemical, serum, molecular - biological, immunological ), analysis of history of illnesses of patients, is statistical methods .First in Ukraine the study of efficiency of ПВТ is conducted by a пегилированным interferon in combination with рибавирином for patients with to - by the infection of HIV / ВГС, taking into account influence of factors, related to ВГС- by the infection : of genotype of ВГС, of the viral loading РНК ВГС in plasma of blood and determination of level of influence of clinical and immunological factors, related to HIV - infection, on efficiency of treatment of ВГС- infections.Study of influence of factors : demographic and epidemiology(sex, age, way of infecting HIV), characterizing ВГС- infection( genotype of ВГС, starting level of the viral loading РНК ВГС in plasma on beginning of ПВТ ) on efficiency of ПВТ for patients with to - by the infection of HIV / ВГС .Study of efficiency of ПВТ( ПегИФН and with рибавирином ) chronic ВГС- infections for patients Вич-инфекцией through the estimation of next indexes : of СКО in the moment of completion 48 - a( or 72 - a, week's on certain criteria ) week's course of П Product Description popup.authors Антоняк С. М. Гетьман Л. І. Коломійчук Л. А. Ничипоренко Л. С. Супруненко Т. В. Федорченко С. В. popup.nrat_date 2020-04-02 Close