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Information × Registration Number 0215U001227, 0112U001282 , R & D reports Title Construction of heterocycles based on the reagents, obtained from arenediazonium salts popup.stage_title Head Mykola Dmytrovych Obushak, Registration Date 03-02-2015 Organization Ivan Franko National University of Lviv popup.description2 Novel variations of domino reactions with utilization of ortho-substituted aryl azides were established. New reagents in Cu(I)-catalized "click"-reactionsс were studied. The utilization of arylated pyrroles (furans and thiophenes) were investigated as building blocks in molecular design of nitrogen containing and fused heterocycles. New strategy for the annulation by the tetrazole derivatives of pyrimidine's ring was developed. Conditions and regioselectivity of reaction of organic azides with methyleneactive compounds were studied. Drug-likeness in silico screening of synthezized compounds was done. The methods of synthesis of new thiazole derivatives using products anionarylation of functionalized olefins were developed. Product Description popup.authors Горак Юрій Ігорович Литвин Роман Зіновійович Туриця Віктор Володимирович popup.nrat_date 2020-04-02 Close