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0215U001478,
0114U003531
,
Development of fundamental physical and chemical principles of the new substance vector systems of anticancer drugs and the creation of production schedules for its production
Gorbyk Petro Petrovych, Доктор фізико-математичних наук
03-03-2015
Institute of Surface Chemistry of the National Academy of Sciences of Ukraine
Based magnetite stabilized sodium oleate, and nanocomposites synthesized Fe3O4 / hydroxyapatite, created vector system - magnetic fluid containing immobilized drugs cisplatin and doxorubicin. Studied the structural and magnetic properties of nanocomposite particles ferymahnitnyh and magnetite and magnetic colloids based on them suitable for use as a vector of onkoteraphyi. It is shown that the antitumor activity of vector system "cisplatin - magnetic fluid" in vivo, compared with the corresponding characteristics for cisplatin is higher in terms of inhibition of tumor growth by 80 - 100% (without increasing toxic-allergic action platinum drug).
Абрамов М.В.
Васільєва О.А.
Горбикк П.П.
Петрановська А.В.
Пилипчук Є.В.
Туранська С.П.
2020-04-02
Updated: 2025-12-07
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