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Information × Registration Number 0215U002439, 0112U006965 , R & D reports Title Pathomorphologic diagnostics and prognosis of tendency of neoplasms with different localization, taking into account markers of biological features popup.stage_title Head Shpon'ka Igor Stanislavovitch, Registration Date 08-12-2015 Organization State organization "Dnepropetrovsk medikal akademy of Ministry Health Ukraine" popup.description2 The object of study - the morphological and immunohistochemical features of human cancers of different locations. Objective - Development and implementation of differential criteria for pathological diagnosis and prognosis of various forms of tumors, based on a comprehensive study of localization, histological structure and immunophenotype process. Research methods - histological, immunohistochemical, and morphometric statistics. Methods of research aimed at determining the range and level of expression of immunohistochemical markers in tumors of different histogenesis and localization, to compare them with each other and with those of previous studies, and further statistical analysis of the results. Preparation immunomorfologicheskie criteria diagnosis and prognosis of cancer to select a rational method of treatment depending on the level of expression of immunohistochemical markers in tumor cells, tissue fragments; This increases the efficiency of the therapy because of decrease in the number of complications from the treatment and the frequency of relapses; reducing the time of treatment and improving the 5-year survival rate. The results of research implemented in the health sector, which is confirmed by information letters №350-2014 "method for predicting the clinical course of squamous cell carcinoma of the oropharynx" and №235-2015 "method for diagnosing gastrointestinal stromal tumors." Applications: medicine (oncology, pathological anatomy). Product Description popup.authors Алєксєєнко Олександр Адольфович Бондарева Валентина Олександрівна Гриценко Петро Олексійович Пославська Олександра Володимирівна Скорик Валерія Русланівна Шинкаренко Тимофій Вікторович Шпонька Ігор Станіславович popup.nrat_date 2020-04-02 Close