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Information × Registration Number 0215U003026, 0112U002411 , R & D reports Title To investigate biochemical ground of changes of endocrine regulation of bone structures in children with the acute leukemia, which were exposed to ionizing radiation due to the Chernobyl accident popup.stage_title Head Bruslova Ekaterina Mihailovna, Registration Date 15-01-2015 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Study object: 520 children (109 patients with acute leukemia, 411 - control group). Aim: to investigate the pathogenesis of bone structures disorders in children who developed acute leukemia in conditions of chronic exposure to ionizing radiation, caused by the Chernobyl accident, based on the study of biochemical mechanisms of endocrine regulation with the aim of development of correction methods. Research methods: clinical, immunological, biochemical, cultural, biophysical, statistical. The pathogenesis of bone methabolism disorders in children with acute leukemia exposed to ionizing radiation as a result of the Chernobyl accident was investigated, the progress of leukemia, bone metabolic indices and changes in the endocrine regulation were revealed, methods for correcting were developed and their effectiveness was assessed. Product Description popup.authors Ільєнко І.М. Базика Д.А. Володіна Т.Т. Гончар Л.О. Кузнєцова О.Є. Ляшенко Л.О. Пушкарьова Т.І. Цвєткова Н.М. popup.nrat_date 2020-04-02 Close