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Information × Registration Number 0215U004758, 0110U006660 , R & D reports Title Development of etiopathogenetic treatment of upper respiratory tract and ear assessment of their effectiveness position evidence-based medicine popup.stage_title Head Pukhlic Sergei Micxailovich, Registration Date 01-12-2015 Organization Odesa National Medical University popup.description2 The object of this study - 792 patients with allergic diseases of the upper respiratory tract of 156 patients with infectious and inflammatory diseases of the nose and paranasal cavities and neck tumors of 190 patients, mostly pharyngoconjunctival parafaringealny area. The study revealed that in 86,2 ± 8,2% of patients with acute rhinosinusitis bathing season found fungi Aspergillus niger, which suggests that the AFS can be induced by a fungal flora which can play a leading etiological role. The most informative criterion of immunological parameters in patients with AS as a change in the level of total IgE, and specific IgE in relation to fungal allergens. Also, there is a decrease in the level of cytokine regulatory factor and the anti - ?-interferon, can indirectly testify in favor of changes in the differentiation of T helper (Th) cells towards Th2, ensuring the formation of immune responses against fungal flora. . Product Description popup.authors Євчев Федор Дмитрович Богданов Кирило Георгійович Дєдикова Ірина Володимирівна Довженко Андрій Вікторович Піонтковська Марина Борисівна Пухлік Сергій Михайлович Тітаренко Ольга Валентинівна Тагунова Ірина Кимівна Чернишева Інна Едуардівна Щелкунов Анатолій Петрович popup.nrat_date 2020-04-02 Close