Search academic texts

Information × Registration Number 0216U000937, 0112U000982 , R & D reports Title Optimization of combined anesthesia during surgery popup.stage_title Head Pavlov O.O., Registration Date 18-03-2016 Organization The Kharkiv Post-graduate Medical Academy popup.description2 Objective: to improve patient outcomes, operated by improving anesthetic tactics. Methods: must be used in a set of clinical and biochemical parameters of system and peripheral hemodynamics, oxygen transport system. The results of the research studied in detail, that the influence of hemodynamic fluctuations caused by reperfusion period, the main factor of perioperative complications of reconstructive operations on the aorta. It is proved that with the use of epidural anesthesia Continued hemodynamic fluctuations are leveled at stages of surgical intervention. It is proved that the increased pace of arterial infusion of support and vazoplegii, which is due to attractive blockade, epidural anesthesia is achieved, it eliminates the effects of mechanical action during clamping and further restoration of blood flow in the aorta. It is confirmed that the stability of the oxygen budget in the perioperative period depends on effective volemic load, ensures the stability of systemic hemodynamics in the reconstruction of the aorta. The study clarified the scientific data on the mechanism of action of epidural neyrolizisu chemical that is demyelination of nerve fibers in the first three months of action. Improved scientific justification for prolonging pain due to permanent activation of pain receptors in systemic administration of narcotic analgesics. Refinement of scientific evidence paradoxical reactions that decrease the functional activity in patients with postoperative opioid analgesia parenteral application, positively affects their emotional state. While the growth of the functional activity of patients in the postoperative period in the application of epidural chemical neyrolizisu accompanied by negative psycho-emotional coloring. The studies and the results obtained allowed to scientifically substantiate the feasibility and efficiency of the use of epidural chemical neyrolizisu in patients with colorectal cancer stage III-IV. Refinement of scientific data on the mechanism of the development of local ischemia / reperfusion in the formation of atherosclerotic vascular lesions of the lower extremities, which is to change the characteristics of the blood flow in the peripheral areas of the systemic circulation. For more information about the process of compensation of peripheral blood flow, which is realized by increasing the speed performance while reducing the volume of blood flow, and aims to support the metabolic processes below the peripheral vascular occlusion. Supplemented by scientific data on the prognostic significance of neutrophil obturation intravazalnogo space as a marker of reperfusion syndrome, and as a result changed the rheological properties of peripheral blood flow, which is the basis of occlusive arterial disease of the lower extremities. The theoretical justification for regional blockade of the femoral nerve as a means of hemodynamic patronage of peripheral blood flow in the surgical treatment of atherosclerotic vascular lesions of the lower extremities. Refinement of scientific data on the protective effect on the emotional state of patients elongated perineural femoral nerve blockade, due to a generalized improvement in metabolic, rheology and functional characteristics of the distal blood flow in patients after surgical correction of occlusive vascular lesions of the lower extremities. Product Description popup.authors Білоусов А.М. Кабаков Б.О. Щур О.І. popup.nrat_date 2020-04-02 Close