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Information × Registration Number 0216U000938, 0110U002438 , R & D reports Title Diagnostics and treatment of oncourological diseases popup.stage_title Head Antonyan Igor, Registration Date 18-03-2016 Organization The Kharkiv Post-graduate Medical Academy popup.description2 The high efficacy and safety of surgical strategy of the implementation of thrombectomy before the renal artery ligation was demonstrated. It's results did not depend on the tumors spread, were not accompanied by deterioration of oncological parameters, and significantly exceeded the effectiveness of standard procedures in terms of feasibility and safety. The study presented feasibility of a new surgical maneuver - creation of a cross-tunnel under the major hepatic veins in 80% and 50% (p> 0,087) patients according to the anatomical and clinical researches. The highest efficiency of T-shaped diaphragmotomy among other approaches to the supradiaphragmatic IVC through the abdominal cavity was demonstrated. The results of nephron sparing surgery in 25 patients with RCC and neoplastic venous thrombosis demonstrated feasibility of this method. The overall level of the perioperative complications of that surgical approach did not differ from the frequency of complications after nephrectomy, and oncological parameters exceeded the results in patients from nephrectomy group. Immunohistochemical profile of the renal cell carcinoma with macroscopic intravenous invasion demonstrated high levels of MMP-9 (100%) and VEGF (92,2%). Multivariate analysis has demonstrated the statistical significance of only one parameter - the level of IVC tumor thrombus. Product Description popup.authors Беєлов Владислав Юрійович Бухмін Олексій Вячеславович Зеленський Олександр Іванович Зеленський Роман Олександрович Мегера Валерій Вікторович Россіхін Василій Вячеславович Рощін Юрій Володимирович Стцишин Роман Васильович Туренко Ігор Анатолійович Шусь Артур Всеволодович Щукін Дмитро Володимирович popup.nrat_date 2020-04-02 Close