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Information × Registration Number 0216U002859, 0111U008679 , R & D reports Title Age-dependent features of pathogenesis of internal organ diseases. Pathogenetic ways of treatment. popup.stage_title Head Rikalo Nadiya Anatoliivna, Registration Date 15-12-2016 Organization Dovganeuk Inna popup.description2 Research is devoted to the study of age-pathogenesis of acute and chronic diseases of organs and tissues, including the toxic hepatitis of various etiologies .. established that the use of toxic factors is highly alteration of diploid hepatocytes set of DNA and increase the level of DNA fragmentation cells and kidney cortex liver tissue. Strengthening reparative regeneration of liver cells in their damage mechanism is mainly polyploidization. It is established that, given the toxic liver damage in rats an increase of syndromes of cytolysis, cholestasis and liver dysfunction. All animals increased fragmentation of nuclear DNA inhibition of hepatocyte synthetic processes in their nuclei and prevalence polyploidization processes. Product Description popup.authors Андрощук Ольга Василівна Береговенко Юлія Михалівна Гумінська Ольга Юріївна Пилипонова Вікторія Володимирівна Полінкевич Сергій Генадійович Романенко Ірина Володимірівна Яровенко Людмила Олександрівна popup.nrat_date 2020-04-02 Close