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Information × Registration Number 0216U003068, 0110U000694 , R & D reports Title Molecular chaperon as a universal regulators of stress-indused signalling pathways cardiomyocytes popup.stage_title Head Sidorik L.L., Registration Date 12-01-2016 Organization Institute of Molecular Biology and Genetics popup.description2 A functional complex were envisaged as potentially interacting as amino acid residues in the molecule chaperone Hsp60 and cardiac- kinase isoforms Akt1 using bioinformatics methods. For the first time we have shown in vivo complex formation between Hsp60 molecular chaperone and kinase Akt1 using the method of cross-imunoretsypitation as in normal myocardium and the conditions of disease, which may indicate a possible role in the regulation Hsp60 by kinase Akt1 activity in the progression of heart failure. Akt1 kinase expression were not found significant changes in expression level changes at low level of activityin cardiomyocytes of total lysates. Product Description popup.authors І.В. Крупська Бобик В.І. Вігонтіна О.Г. Заєць В.М. Маркелова О.Ю. Яковенко Л.Ф. popup.nrat_date 2020-04-02 Close