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Information × Registration Number 0216U007300, 0110U006269 , R & D reports Title Ion channels and calcium homeostasis as the targets of modulatory influence of endo- and exogenous biological active substances. popup.stage_title Head Shuba Yaroslav M., Доктор біологічних наук Registration Date 04-07-2016 Organization International center of molecular physiology popup.description2 To conduct phase of the Project it was decided to study intracellular concentrations of calcium ions ([Ca2 +]i) in rat splenocytes, thymocytes and Jurkat cells stimulated by corpuscular antigen of golden staphylococci strains Wood-45 and staphylococcal toxoid using calcium-sensitive fluorescent dye Fura-2AM . We have shown that corpuscular antigen of Wood-45 in concentrations of 60 mg/L increased cytoplasm concentrations of calcium ions in 40% ± 8% splenocytes by 38% as initially level on average. Reacting cells were identified as lymphocytes. Staphylococcal anatoxin with concentrations of 60 units/L and staphylococcal corpuscular antigen staphylococci strains Wood-45 with concentrations of 60 mg/L increased cytoplasmic calcium concentrations in 24% ± 4% of thymocytes.The studied substancesdid not affect Jurkat cells. Product Description popup.authors Морєв Р.М. Соткіс Г.В. Шуба Я.М. popup.nrat_date 2020-04-02 Close