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Information × Registration Number 0217U004842, 0116U002209 , R & D reports Title Genetic and biochemical aspects of the regulation of some catabolic and anabolic processes in microorganisms: alcoholic fermentation, catabolism of methanol, biosynthesis of flavins, glycerol, hydrogen and glutathione popup.stage_title Head Sibirny Andriy Andrijovych, Registration Date 09-03-2017 Organization Institute of cell biology, National Academy of Sciences of Ukraine popup.description2 New methods of selection of Saccharomyces cerevisiae mutants , capable of increased production of ethanol during fermentation using oxythiamin, trehalose, 3 brompiruvate glyoxalic acid and glucosamine were developed. Selected mutants with increased 10-12% production of ethanol can be used in industrial production of ethanol. A new specific regulator of alcoholic fermentation of xylose Cat8 in yeast Hansenula polymorpha was identified . CAT8 gene deletion in improved ethanol producer increased the production of alcohol up to 12.5 g / l under xylose fermentation at 45 ° C. The role of peroxisomal enzymes dyhydroxyacetonsynthase and transaldolase in alcoholic fermentation of xylose in H. polymorpha yeast was discovered. Increased expression of these enzymes led to increased production of ethanol to 12 g / L during alcoholic fermentation of xylose at elevated temperature. It was found that enhance gene expression GCY1 that encodes glyceroldehydrogenase in yeast H. polymorpha, led to increased production of ethanol from glycerol. The highest level of ethanol production reached 8.5 g / l during fermentation of glycerol. Product Description popup.authors Булботка Н. Василишин Р. Гринів О.Б. Дмитрук К.В. Куриленко О.О. Левків К.О. Лизак О.О. Лужецький Т.Б. Муращенко Л. Рачкевич Н. Семків М.В. Фаюра Л.Р. Федоренко В.О. Федорович Д.В. Цирульник А.О. Юрків М. popup.nrat_date 2020-04-02 Close