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Information × Registration Number 0217U006616, 0117U003204 , R & D reports Title Structural control of the reaction direction. Controlled synthesis as the basis for innovative chemical technology popup.stage_title Head Bogza Sergij Leonidovich, Доктор хімічних наук Registration Date 24-11-2017 Organization The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry popup.description2 The object of study - 2-aminoindolyzine derivatives, their synthesis and transformation to . The aim of the work is to develop synthetic approaches for the nitrogen containing monoheterocycles aannelation to pyrrole core of indolizine system. Methods of investigation - organic synthesis, thin-layer chromatography, 1H NMR, 13C NMR IR, UV spectroscopy, chromatographic mass spectrometry, X-ray diffraction analysis, elemental analysis. At firstly conditions for polyheterocyclic compounds synthesis was obtained for annelation pyridine, pyrimidine or thiazepine core under mono- or binucleofiles action. Regioselectivity these interactions was shown. The results of the work may be useful in the preparative chemistry of heterocyclic compounds - biologically active substances and the development of new drugs based on them. Product Description popup.authors Богдан Н.М. Хайрулін Андрій Рашидович popup.nrat_date 2020-04-02 Close