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Information × Registration Number 0219U003079, 0117U001046 , R & D reports Title The development of programs for personalized control of the dose absorption during radiation therapy of tumors of the genitals, head and neck tumours using in vivo dosimetry popup.stage_title Head Starenkiy V.P.; Sukhina O.M., Доктор медичних наук Registration Date 18-01-2019 Organization State Organization "Grigoriev Institute for Medical Radiologiy of the National Academy of Medical Sciences of Ukraine" popup.description2 Object of the study: radiation therapy of malignant tumors of female genitalia, head and neck using in vivo dosimetry. The aim of the study: to increase the effectiveness of radiotherapy for genital, head and neck cancer by optimizing topometric preparation using in vivo dosimetry to ensure the quality of radiotherapy. Instrumental methods and equipment: X-ray, morphological, clinical-instrumental, statistical, gamma-therapeutic device ROKUS-AM with Со-60 source (Egamma = 1,25 MV), linear accelerator "Clinac-600C", universal clinical dosimeter "UNIDOSE-E", planning system Eclipse 8.9, X-ray computer tomograph "Toshiba Aquilion 16", simulator "Acuity". Theoretical and practical results: approaches to the correction of the radiation therapy plan were proposed depending on the constitutional features of patients, the type of irradiation and the localization of irradiation fields. It has been proved that repeated planning in patients with oncogynecological pathology reduces the median deviation of the dose from 0.14 to 0.05 %, which constituted of 64.3 %. Scientific data on the incidence and nature of radiation reactions of organs that are a part of the radiation zone under conventional and modified methods of conformal radiation therapy were supplemented. The technique of pre-radiation preparation to the irradiation of tumors of the head and neck with the use of a tongue fixator while taking into consideration the artifacts on tomographic images has been developed. Novelty: the regularity of deviation between the planned dose and the results of in vivo dosimetry was determined depending on the constitutional features, the type of irradiation, the localization of irradiation fields; the influence on critical organs and quality of life of patients was estimated. Efficiency of implementation: reduction of the period of hospitalization for 3-7 days and the cost of treatment of radiation reactions over 3000 UAH. Field of application: radiation therapy, oncology. Product Description popup.authors Авер'янова Л.О. Аврунін О.Г. Артамонова Н.О. Артюх С.В. Васильєв Л.Л. Грищенко Т.П. Пшишевська Л.А. Сімбірьова А.С. Самофалов І.О. Свинаренко А.В. Старенький В.П. Сухіна О.М. Трофімов А.В. popup.nrat_date 2020-04-02 Close