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Information × Registration Number 0219U003173, 0116U001304 , R & D reports Title Improvement of the diagnosis and treatment of infectious-associated recurrent obstructive bronchitis with herpesvirus infection popup.stage_title Head Rudenko Antonina Alekseevna, Yukhimenko Olga Alekseevna, Registration Date 24-01-2019 Organization The L.V.Gromaschevskyi Scientific and Research Institute of Epidemiology and Infectious Diseases popup.description2 It was established that the broncho-obstructive syndrome on the background of ARF deploys at 1.46 ± 0.59 day. The presence of broncho-obstructive syndrome significantly prolonged the course of acute respiratory insufficiency. The factors leading to an increase in the propensity to develop broncho-obstruction against the background of acute respiratory infections were increased proinflammatory activity with the simultaneous inhibition of anti-inflammatory mechanisms of the immune system of the respiratory tract. Spirometry is an informative method for determining the presence of bronchial obstruction, with the exception of young children. It is established that in the development of acute respiratory diseases obstructed by obstructive syndrome, the association MZEIZ and UMP is important. The MESEZ and UPM spectrum has differences in OSD, and also with BOS and ROB. This can be used as additional criteria for diagnosis of HRD OS and prediction of recurrent episodes OS. It has been found that increased risk of proinflammatory cytokines (IL-1, IL-6,) and IL-8 and decreased levels of anti-inflammatory interleukin (IL-10) are registered in both the exacerbation period and the remission period. It has been established that in children with infectious-associated RBD, compared with children with RBD of allergic genesis and ultrasound, the replication of the Epstein-Barr virus (EBV) is likely to increase. It is established that the traditional scheme of treatment of acute respiratory infections is not effective, because it does not take into account some features of the pathogenesis of acute respiratory system, in particular the microbial landscape, negative changes in the immune system, and peroxidation processes, as a result of its use remain in the initial state or amplified. It also does not reduce the number of repetitive episodes. The most effective treatment scheme for ARI treatment is proposed, which includes, in addition to traditional therapies, the course of antibiotics, immunocorrectors and antioxidants. Product Description popup.authors Дьяченко Павло Анатолійович Замалеєва Катерина Петрівна Клюс Вікторія Юріївна Муравська Любомира Василівна Пархомаць Богдан Анатолійович Руденко Антоніна Олексіївна Тарасова Ірина Анатоліївна Юхименко Ольга Олексіївна popup.nrat_date 2020-04-02 Close