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Information × Registration Number 0219U003255, 0116U000363 , R & D reports Title To improve diagnosis and methods of treatment of patients with malignant tumors ENT with regional metastasis popup.stage_title Head Lukach Ervin Vencelovich, Доктор медичних наук Registration Date 30-01-2019 Organization Kiyv Research Institute of Otolaryngology named after prof. O.S.Kolomiychenko popup.description2 Improvement of diagnostics and surgical treatment of patients with cancer of the upper respiratory tract has been studied. The frequency and localization of neck metastatic lymph nodes (LN) in patients with upper respiratory tract cancer is investigated. It has been established that metastases in the neck LN were histologically confirmed in 61.9% of operated patients with laryngeal and pharyngeal cancer. The presence or absence of an expression of the Human Papillomavirus P16 marker in tumor tissue does not affect the duration of a non-recurring period in patients with pharyngeal and laryngeal cancer. The two-year overall survival rate of patients after treatment was 86%. The possibility of differential diagnosis between unchanged and metastatic NI of the neck in patients with cancer of the upper respiratory tract with the use of elastography is determined. The specificity of the method of transient wave elastography was 84% and significantly differed from that in the gray-cardiac ultrasound scan at 69% (Х2 = 6.112; p <0.05) and with compression elastography at 64% (Х2 = 10.162; p <0.05). It was morphologically established that the highest levels of elastographic density corresponded to metastases of squamous cellulite cancer with the presence in its structure of cells of moderate and significant keratinization of tumor parenchyma. he data on the patterns of the distribution of a cancer in the limits of LN, which allows to carry out the purposeful morphological search of micrometastases, is received. The technique for reconstruction of the carotid artery defect after the removal of the tumor for restoration of blood flow through the main vessel has been improved. Methods have been developed to prevent complications after the removal of malignant tumors of the larynx, which can protect the main vessels, which greatly improves the rehabilitation of such patients. Product Description popup.authors Діхтярук В.Я. Клочков Є.І. Павлик Б.І. Сережко Ю.О. Стрежак В.В. Цимбалюк Є.М. popup.nrat_date 2020-04-02 Close