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Information × Registration Number 0219U102224, 0119U102701 , R & D reports Title Engineering of xylose transport in the thermotolerant yeast Ogataea polymorpha for improvement of alcoholic fermentation popup.stage_title Head Sibirny Andriy A., Доктор біологічних наук Registration Date 23-12-2019 Organization Institute of Cell Biology popup.description2  To improve xylose utilization efficiency in the yeast O. polymorpha the modified Hxt1 protein was constructed by substitution of asparagine to alanine at position 358 and replacement of N-terminal lysine residues predicted to be the target of ubiquitination for arginine residues. The modified version of Hxt1 was introduced into genome of O. polymorpha advanced ethanol producer from xylose obtained by metabolic engineering approaches. The overexpression of the modified Hxt1 resulted in simultaneous utilization of both glucose and xylose during fermentation in the obtained O. polymorpha recombinant strains. Product Description popup.authors Vasylyshyn Roksolana V. Kurylenko Olena O. popup.nrat_date 2020-04-02 Close