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Information × Registration Number 0221U103348, 0116U000224 , R & D reports Title To study the biological properties of bacteriophages (pio- and enterophagous) and develop scientific principles of their use in the system of epizootic welfare of fur-bearing animals and pets popup.stage_title Head Zavhorodnii Andrii І., Доктор ветеринарних наук Registration Date 18-02-2021 Organization National Scientific Center Institute of Experimental and Clinical Medicine popup.description2  Object of research - the spread of bacterial diseases of the gastrointestinal tract of fur-bearing animals and domestic animals; biological properties of isolated bacteriophages of skin pathogens. The aim of the work is to investigate the prevalence of bacterial diseases of the gastrointestinal tract of fur animals and domestic animals and to study the biological properties of isolated bacteriophages for the purpose of 'ix selection'. Research methods - bacteriological, clinical and epizootological, statistical. The taxonomic composition of pathogens of bacterial diseases of the gastrointestinal tract of fur-bearing animals, dogs and cats has been established As a result of the performed researches, 4 strains of Staphylococcus phages and 2 strains of Proteus were isolated and the most promising isolates of bacteriophages S9, S10 capable of lysing Staphylococcus spp. Were selected. and bacteriophage Prtl - Proteus vulgaris. Phage S10 had the widest spectrum of lytic activity relative to the studied cultures of the genus Staphylococcus, which lysed 66.6% of strains. Based on the results of the research, Methodical recommendations for the isolation of bacteriophages from the clinical material and determination of biological properties have been prepared. The technology of bacteriophage cultivation and methods of their purification have been developed. and its titer exceeded the original more than 5 times and the rules of treatment of animals with a drug developed from lysing phages based on bacteriophages of strains of the genera Staphylococcus, Streptococcus and Proteus. The methodology of phage preparations application in the system of ensuring epizootic well-being of fur animals and domestic animals taking into account the pathogenesis of bacterial diseases and methods of keeping animals is formed. Product Description popup.authors Keleberda Mykola I. Oleshko Andrij Yu. popup.nrat_date 2021-02-18 Close