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Information × Registration Number 0221U103638, 0116U004025 , R & D reports Title Coordination and medicinal chemistry of mono-, bi-, heterometallic and mixed-ligand complexes of the "metals of life" (Fe, Co, Cu, Mo) and cytostatics (Pd, Rh, Ru, Ga) with modified, biologically related and bioactive molecules with antineoplastic, antiviral and antiresorptive action. popup.stage_title Head Pekhnyo Vasyl I, Доктор хімічних наук Registration Date 23-02-2021 Organization Institute of General and Inorganic Chemistry. VI Vernadsky National Academy of Sciences of Ukraine popup.description2 According to the research topic, 125 new coordination compounds (mononuclear, heteronuclear, molecular, cationic, etc.) with 28 ligands of different types (listed above) were obtained. The structure of 45 complexes was established by X-ray diffraction method. The antitumor activity of 6 complexes of Pd (II) and Pt (II) with bisphosphonic acids and functionally substituted carbothioamides was established, which after a full cycle of tests can be recommended as a basis for antitumor drugs.  Product Description popup.authors Ilnytska Olena L. Borovyk Polina V Vakarov Serhii V. Denysenko Iryna M Dzyuba Valeriy I. Dovbii Yan M. Koval Lyudmila I. Kozachkova Oleksandra M Orysyk Svitlana I Selin Roman O. Tretyakova Irena M. Fedosova Natalia M. Chernii Victor Ya Chornenka Nina V. Shtokvish Olgert O popup.nrat_date 2021-02-23 Close