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Information × Registration Number 0221U104876, 0120U104126 , R & D reports Title Use of electrochemical biosensors and fluorescent probes for analysis and improvement of 3D bioprinted tissue structures. popup.stage_title Head Tananaiko Oksana Yu., Кандидат хімічних наук Registration Date 25-04-2021 Organization Taras Shevchenko National University of Kyiv popup.description2 Objects of research - associates of surfactants (surfactants) with fluorescent reagents rhodamine C, rhodamine 6G and eosin; nanostructured planar carbon electrodes modified with composite materials based on manganese oxide (IV), copper (II) oxide and glucose oxidase enzyme immobilized in a silicon oxide film. The purpose of the work is to develop optical and fluorescent probes based on rhodamine dyes to study the properties of organized supramolecular model media based on nonionic surfactants; development of electrochemical sensors based on modified with composite films SiO2-MnO2 and SiO2-CuO planar electrodes for detection of glucose and hydrogen peroxide as products of vital activity of immobilized biological cells. Research methods - cyclic voltammetry (measurements were performed on a potentiostat company PalmSens EmStat 2 (Netherlands) using a three-electrode cell based on nano PVE); to study the morphology of the surfaces used the method of scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) measurements were performed on the device Tescan Mira 3 LMU scanning electron microscope, the company "Tescan" (Czech Republic); registration of fluorescence spectra was performed using a fluorescent spectrometer PerkinElmer LS 55; the acidity of the solutions was monitored with a pH meter "pH 340" with a glass electrode ESL-43-07. The parameters of modification of planar nanostructured electrodes with composite coatings based on manganese dioxide or copper (II) oxide and glucose oxidase encapsulated in SiO2 film were developed and optimized. MnO2 particles were obtained by electrochemical deposition on the electrode surface. CuO particles were synthesized by hydrothermal synthesis. A biocomposite SiO2 film with encapsulated enzyme and CuO particles was applied to the electrode surface by electro-induced deposition.  Product Description popup.authors popup.nrat_date 2021-04-25 Close