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Information × Registration Number 0221U105842, 0120U104785 , R & D reports Title Polypharmacophoric organic compounds based on peptidomimetics and annelated benzodiazepines popup.stage_title Head Chebanov Valentyn A., Доктор хімічних наук Registration Date 06-09-2021 Organization State Scientific Institution Scientific and Technological Complex" Institute of Single Crystals "of the National Academy of Sciences of Ukraine popup.description2  At the second stage of the work new and improved methods of synthesis of the intermediates and the target compounds were developed, physicochemical properties of synthesized compounds were studied, spectral and chromatographic researches were carried out. Pharmacophore models of Abl protein kinase receptor and cannabinoid receptors CB1 and CB2 have been developed. The solubility of the synthesized compounds was studied in accordance with the requirements of the State Pharmacopoeia of Ukraine and the membranotropic action of the synthesized compounds and their influence on the structure and microviscosity of model lipid membranes were studied Product Description popup.authors popup.nrat_date 2021-09-06 Close