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Information × Registration Number 0221U106770, 0120U104116 , R & D reports Title Effect of ioninizing radiation on the amino acid molecules structure popup.stage_title Head Snihurskyi Oleksandr V., Доктор фізико-математичних наук Registration Date 20-12-2021 Organization Institute of Electronic Physics of the National Academy of Sciences of Ukraine popup.description2 SRW report: 122 p., 43 fig., 6 tab. The objects of research - physical phenomena initiated by the interaction of electrons of a wide energy range of with biologically relevant molecules. The subjects of research - the amino acid molecules threonine and tyrosine. The aim of the work is to study the processes of threonine and tyrosine molecules destruction under the action of a wide energy range ionizing radiation, their fragments formation, finding geometric and energy parameters of this process, establishing mechanisms of inter-molecular bond decay with new atomic and molecular compounds formation. Research methods and experimental equipment – complex experimental and theoretical studies of single and dissociative ionization of threonine and tyrosine molecules, careful unambiguous identification of these molecules decay products enhanced by a wide energy range electrons, finding the ratio of their mass to charge and establishing their chemical composition. Experimental studies were performed using the technique of beams of monoenergetic electrons and molecules with the involvement of modern methods of high-resolution mass spectrometry. Results and novelty: – The mass spectra of threonine and tyrosine molecules formed during the ionization of a tyrosine molecule by electron impact at three radiation doses (0, 5 and 20 kGy) hav st been investigated. Most of the observed peaks have been identified, their chemical compositions have been determined. – The appearance energies of the main ionic fragments of these amino acid molecules have been experimentally measured and theoretically calculated. – Using a number of theoretical approximations and approaches, the cross sections of elastic electron scattering, electron impact ionization, viscosity, and momentum transfer have been calculated for the threonine and tyrosine amino acid molecules. –The main mechanisms of fragmentation of of threonine and tyrosine molecules at different radiation doses have been established. Product Description popup.authors Vukstych Vasyl S. Remeta Yevhen Yu. Romanova Liudmyla H. popup.nrat_date 2021-12-20 Close
R & D report
Head: Snihurskyi Oleksandr V.. Effect of ioninizing radiation on the amino acid molecules structure. (popup.stage: ). Institute of Electronic Physics of the National Academy of Sciences of Ukraine. № 0221U106770
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