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Information × Registration Number 0222U000788, 0120U104348 , R & D reports Title Improvement of therapeutic diagnostic technologies and biosecurity measures of mono - and mixed tick - borne infection. popup.stage_title Head Andreychyn Mykhailo A., Доктор медичних наук Registration Date 18-01-2022 Organization I. Horbachevsky Ternopil State Medical University popup.description2  GDR report (intermediate): 54 pages, 15 figures, 13 tables, 25 sources. LYME-BORELIOSIS, IXODE TICKS, B. BURGDORFERI SENSU LATO (B. BURGDORFERI SENSU STRICTO, B. AFZELII AND B. GARINII, B. SPIELMANII) , ERYTHEMIC FORM OF LYME BORRELIOSIS, UNDERHYTHEMIC FORM OF LYME BORRELIOSIS, ELISA, IMMUNOBLOT, MULTIPLEX INDIRECT IMMUNOFLUORESCENCE REMOTE Object of research: Ixodes mites, selected from patients and from the environment of 7 regions of Ukraine; patients with erythematous and non-erythematous forms of Lyme borreliosis with lesions of the cardiovascular system (CVD), nervous system (NA) and musculoskeletal system (MSS), morphea. Purpose: to establish the frequency of natural infection of ticks selected from humans, animals and the environment of 7 regions of Ukraine: Ternopil, Lviv, Volyn, Rivne, Khmelnytsky, Vinnytsia and Zhytomyr B. burgdorferi s. l., A. Phagocytophilum, B. miyamotoi and Babesia spp .; apply ELISA and EUROLINE Borrelia RN-AT adv immunoblot to determine the involvement of B. burgdorferi s.l. (B. burgdorferi s.s., B. garinii, B. afzelii, B. spielmanii) to clinical manifestations of LB in patients with CCC, NA and ORS; determine the content of specific IgM and IgG antibodies to B. miyamotoi and the concentration of immunoglobulins of classes A, M, G and E in the sera of different segments of the population; use the method of multiplex indirect immunofluorescence to diagnose antibodies to a number of infectious sparrows that may be involved in lymphadenopathy, CCC, ORS and skin; apply the method of remote thermography to study the temperature difference ((T) of the affected and healthy areas of skin in patients with EF LB before and after etiotropic treatment of the disease, including depending on the dissemination of the process. Product Description popup.authors popup.nrat_date 2022-03-09 Close