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Information × Registration Number 0222U001214, 0119U001081 , R & D reports Title To study the state of the system of growth hormone / growth factors in children and adolescents, depending on the availability of vitamin D popup.stage_title Head Bolshova Olena V, Registration Date 24-01-2022 Organization State Institute "V.P. Komissarenko Institute Of Endocrinology And Metabolism of The National Academy of Medical Science of Ukraine" popup.description2  A method of increasing growth to target values in prepubertal people with short stature, which is a consequence of intrauterine growth retardation, has been developed. When using this technique in patients there was an acceleration of growth rate by 0.7 cm (p <0,05). The increase in growth after 6 months on somatotropin therapy with the addition of vitamin D averaged 5.82 ± 0.14 cm (increase in growth only on somatotropin therapy was 5.12 ± 0.19 cm) (p <0.05). This was manifested both by an increase in the level of vitamin D in the blood plasma and by an increase in the level of insulin-like growth factor-1, which is a recognized marker of treatment effectiveness. Product Description popup.authors Bolshova Olena V Vyshnevska Olga Anatoliivna Kvachenyuk Dmytro Andriyovych Lukashuk Iryna viktorivna Malynovska TetyanaMykolaivna Muz Nataliya Mykolaivna Samson Oksana Yaroslavivna Sprynchuk Nataliya Andriivna popup.nrat_date 2022-03-09 Close