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Information × Registration Number 0222U001514, 0118U100224 , R & D reports Title The studying of nutrition influence on desynchronosis in people with metabolic risk factors popup.stage_title Head Romanenko Mariana S, Кандидат медичних наук Registration Date 28-01-2022 Organization State institution "D. F. Chebotarev Institute of Gerontology National Academy of Medical Sciences of Ukraine" popup.description2 Systemic deterioration of metabolic profile in middle-aged men with a history of night shifts after 35 years, which was accompanied by negative changes in the structure of the diet - increased (46%) fat content, which may also be a factor in desynchrony. Insomnia has been associated with a deterioration in the metabolic profile in middle-aged and elderly men, as well as with a greater functional age of the cardiovascular system in the elderly, regardless of gender. The synchronicity of annual rhythms, in particular seasonal differences, the content of the main types of intestinal microbiota, the ratio of which is a marker of metabolic disorders, with the consumption of fiber. Daily differences in body temperature in healthy subjects of different age groups confirm the formation of "age" desynchrony in the aging process. In patients with MS of different ages, daily temperature fluctuations showed dynamics similar to age. However, given the poorer metabolic status of patients, it can be assumed that behind the temperature desynchrony they have other mechanisms that require further research. In healthy elderly people on the background of age-related desynchrony of cardiointerval rhythms, the value of the functional age of the cardiovascular system is most consistent with the calendar age, while in middle-aged and elderly MS there is an increase in functional age of the cardiovascular system by 12 (6-18) and 4 (0-11) years, resp., P <0,05. Adherence to the principles of healthy eating is accompanied by better indicators of the functional age of the cardiovascular system. Adding a drink enriched with iodine and molecular hydrogen to patients' diets improved iodine supply, reduced the progression of metabolic disorders, and prevented an increase in temperature desynchrony. There was an excess of daily fat intake by 54-96% in men and 44-52% in women, protein - by 33-39% in men and 7-18% in women, and a decrease in carbohydrate intake by 9-18% in men and 5-9% of women. Product Description popup.authors Ivanenko Lidiya Danylivna Piven Lyubov Valentynivna Romanenko Mariana Stanislavivna Sinyeok Lyudmila Leonidivna popup.nrat_date 2022-03-09 Close